Malegra is a drug that is used in the treatment of erectile dysfunction and all the problems which are related to it. It is a generic alternative for Viagra – a branded medicine that is also used in the treatment of sexual dysfunction in males. The composition of Malegra is similar to that of Viagra i.e. it consists of sildenafil citrate as its active pharmaceutical agent. This drug is the best for a person who is unable to attain or maintain an erection for a longer period of time which is usually required to experience climax during a sexual intercourse. Sildenafil citrate that is present in the composition of this drug is an inhibitor of Phosphodiesterase type 5 enzyme that produces its effects by acting on the corpus cavernosum of the penis and producing a relaxing effect on it.
The drug is manufactured in the form of compressed tablets and is meant to be taken orally about 30 to 40 minutes before taking part in any kind of sexual activity in order to experience maximum therapeutic effects. Six hours is the estimated biological half-life of this drug. It is to be remembered that Malegra does not have aphrodisiac properties and it cannot induce an erection in males but works on a male that is already aroused sexually making it easier for him to gain a firm erection.
Mechanism of Action of Malegra
Just like Viagra, Malegra consists of sildenafil citrate in its formula. Sildenafil citrate is an inhibitor of an enzyme known as Phosphodiesterase type 5 which is present in different parts of the body including male genital areas like the penis and the prostate gland. Phosphodiesterase type 5 enzyme is responsible for the breakdown of cyclic Guanosine Monophosphate (cGMP), a substance that is required in the corpus cavernosum of the penis to produce an erection. Because PDE5 depletes the amount of cGMP from the penile tissue, it causes sexual dysfunction in males. Sildenafil citrate, when administered inside the body, works against this enzyme to prevent it from degrading cGMP and causes it to accumulate in the penis. Hence, when a person is sexually stimulated, nitric oxide is produced which reacts with cGMP to cause a relaxing effect on the muscles of the corpus cavernosum. Also, it causes a dilating effect on the vessels supplying the penis and helps in opening up the blocked arteries around the genital area. This permits more blood to flow towards the penis and also smoothens the penile muscles causing an erection to occur easily. In addition to this, the drug also exerts its effects in order to recover more quickly after experiencing an ejaculation. The drug works best when a person is already stimulated sexually.
Clinical Indications of Malegra
Penile issues are becoming prevalent among men of almost all age groups which interfere with the normal sexual life of these men and decreases their quality of life. By using some sensational medicines like Malegra, these patients can restore their sexual health and regain their confidence. Malegra is a drug that consists of a potent agent required to produce erections in males who are normally unable to achieve them. This drug is meant to be used in general sexual dysfunction in males who are either not able to achieve an erection or are not able to keep these erections for a longer time. In addition to this, some other forms of Malegra are also used to treat other problems that are usually accompanied with erectile dysfunction. Malegra in every dose is a great generic drug for a person who is not able to complete his sexual activities due to a problem with his sexual health. It is mainly used to sensually arouse a person and this potent medicine is able to produce a great outcome which lasts for a longer period of time hence, meeting the satisfaction level of its user to the maximum possible extent.
How to Consume Malegra
Malegra is manufactured in the form of hard tablets which are advised to be used via oral route only. A tablet of Malegra must be placed on the tongue and should be swallowed with the help of a full glass of plain water. It is recommended that the users should not crush or break the tablet and the tablets must also not be chewed or sucked on as it can cause irritation in the esophagus. One tablet is enough for a day to experience the desired therapeutic effects. Because the effects of sildenafil last for a couple of hours only, it is advised to use the drug half an hour to 40 minutes prior to engaging in a sexual activity. This margin of 30 to 60 minutes is important and must be kept in mind because sildenafil requires some time to activate itself before producing any results. The presence of sexual stimulation is necessary for Malegra to produce its effects and it would not work in the absence of it. A doctor should be consulted prior to using this drug and the user must be careful not to take more than one dose per day or taking two doses with a very short interval in between.
Different Forms and Strengths of Malegra
One of the many factors that make Malegra better and more convenient for the users to consume is its availability in different forms and potencies. The strengths of Malegra are varied according to the concentration of sildenafil citrate present in the. 25 mg tablet of Malegra is the form with the weakest potency while 50 mg of this drug is the most commonly prescribed form for the patients who are just beginning to start a therapy with it. 100 mg of Malegra is a very strong form of this drug that readily treats the problem of erectile dysfunction among men. In addition to the simple form of Malegra, it is also available in two other formulations which are even more powerful than the basic drug. These forms include Malegra DXT and Malegra FXT which contains 30 mg of Duloxetine and 40 mg of Fluoxetine respectively in addition to sildenafil. These forms of Malegra not only tend to treat the problem of erectile dysfunction in males but also bring improvement in the problem of premature ejaculation experienced by them. These additional components actually decrease the movement of neurons from the penis to the brain which helps in prolongation of their erections. Malegra is also available in the form of oral jellies for those who do not want to take hard tablets for treating their problem.
Malegra 50mg/100mg Side Effects
A very popular and important question that is asked by many of the customers who are wanting to try Malegra for the first time is whether it causes any side effects. This question cannot be answered with full assurance since the behavior of a single drug in multiple different patients is entirely different and unpredictable. Because Malegra is structurally associated with Viagra and consists of the same components, it can be said that it causes the same side effects as those seen while using Viagra. The most common of these side effects include a headache, nausea, and trouble with the stomach of the patient taking it. It can cause indigestion and diarrhea as well. The patient consuming this drug might suffer from a pain in his muscles and bones along with a general sense of weakness prevailing throughout the body. There may be a flushing of the skin of different parts of the body face being the most common of them all.
Tremors can also be seen in some patients while others complain of an irritation in throat and congestion of the nose. In some cases, patients have also reported facing problems with the visual acuity while consuming Malegra and stating the drug as a cause of a decrease in the vision of one or both of their eyes. Similarly, some patients have also experienced from tinnitus (ringing in the ears) along with auditory disturbances. In extremely rare cases, Malegra has also caused a development of priapism i.e. prolonged hard erection of the penis which is extremely painful to bear.
It must be kept in mind that these problems mentioned above can occur with almost every medicine meant for the treatment of erectile dysfunction and are not specified to Malegra alone. It must also be kept in mind that not all of these side effects can occur in a person taking Malegra and the occurrence of these adversities can vary from person to person. There has been a high level of satisfaction from the people who used Malegra but there are some complaints about the side effects caused by some particular batches of Malegra. As reported by some, there have been some cases in which Malegra has proven to be extremely dangerous for some patients causing all the side effects mentioned above in great severity.
Malegra is, no doubt, a great generic version for Viagra because it has a great level of effectiveness and a very low cost which makes it affordable for almost everyone who needs it. A possibility of this drug causing side effects exists but the majority of these side effects experienced by people are minimal and can be seen with any other drug taken for ED. Hence, due to the scarcity of incidences in which Malegra proved to be causing dangerous side effects, it cannot be recommended as an effective drug for ED.